| Acronym | Definition |
|---|
| VPO | Village Post Office (India) |
| VPO | Vienna Philharmonic Orchestra |
| VPO | Vapor Pressure Osmometry |
| VPO | Vantage Point Operations |
| VPO | Vivienda de Protección Oficial (Spain) |
| VPO | Vice President's Office |
| VPO | Volunteer Probation Officer (program) |
| VPO | Variance Purchase Order |
| VPO | Virtual Private Office |
| VPO | Volume Per Outlet |
| VPO | Vendor Purchase Order (sales) |
| VPO | Vice President / Operations |
| VPO | Vanadium Phosphorus Oxide |
| VPO | Visitors Paid Out (hotel accounting) |
| VPO | Volunteer Pilot Organization |
| VPO | Victor's Professionally Organized Construction |
| VPO | Virtual Production Office (various companies) |
| VPO | Virtual Program Office |
| VPO | Victim Protection Order |
| VPO | Virginia Program At Oxford (UK; est. 1967) |
| VPO | Volume, Pressure, Inspired Oxygen |
| VPO | Veterinary Practitioner Only |
| VPO | Voltage Power Optimization (energy industry) |
