| 释义 |
‖ pellagra Path.|pɛˈleɪgrə, -ˈægrə|
[It. and mod.L. (F. pellagre), said to be f. pell-is + ? -agra in chiragra, podagra (gout in the hands, the feet); but perh. orig. It. pelle agra ‘rough skin’.]
An endemic disease (frequent among the peasantry of Southern Europe, esp. Lombardy, often attributed to eating diseased maize), in which the skin reddens, dries, and cracks, and the epidermis peels off in bran-like scales; the digestive organs and central nervous system are affected, and the disease often ends in insanity.
1811Hooper Dict. Med. s.v., The disease called the pelagra does not appear to have been noticed by any of our nosologists. 1840Penny Cycl. XVII. 388/1 Pellagra is a disease chiefly affecting the skin, and particularly prevalent amongst the peasantry of the north of Italy. 1854N. Syd. Soc. Year-bk. Med. & Surg. 176 m, The endemic pellagra of Aragon..is absolutely identical with the endemic pellagra of Asturias. 1865Chambers's Encycl. VII. 363/1 Pellagra, at one time the name of a..skin-disease..is now employed to designate a group of phenomena, of which the most prominent and significant are mental. 1874Bucknill & Tuke Psych. Med. (ed. 3) 364 The first descriptions of pellagra appear about the year 1770.
Hence pellagraˈgenic a., engendering pellagra; peˈllagrin, a person affected with pellagra.
1865Chambers's Encycl. VII. 363/1 Of 500 patients in the Milan Lunatic Asylum in 1827, one third were pellagrins. 1903Brit. Med. Jrnl. 11 July 86 Alcoholism renders the organism more prone to suffer from pellagragenic poison. |
