| Acronym | Definition |
|---|
| LUP | La Última Palabra (Spanish: The Last Word; Mexican TV show) |
| LUP | Land Use Plan |
| LUP | Language Upgrade |
| LUP | Lazy Updates Propagation |
| LUP | Location Update |
| LUP | Live Upgrade |
| LUP | Liberal Unionist Party (UK) |
| LUP | Lunds Universitets Publikationer (Swedish: Lund University Publications) |
| LUP | Liberia Unification Party |
| LUP | Lithuanian Farmer's Party |
| LUP | Lying-Up Point |
| LUP | Kalaupapa, Molokai, Hawaii (airport code) |
| LUP | Letter of Unserviceable Property (USMC) |
| LUP | Lightest U-parity Particle |
| LUP | Last Usage Phase |
| LUP | Link-Up Point |
| LUP | Liste Unique des Problèmes (French: single list of problems) |
| LUP | Low Uniaxial Pressure |
| LUP | Laboratorio de Urbanismo Politico (Montevideo, Uruguay) |
| LUP | Lifeless Undead Phenomenon (science fiction) |
| LUP | Lego Universe Partner (online game) |
