GISS
| Acronym | Definition |
|---|---|
| GISS | Goddard Institute for Space Studies |
| GISS | Geographic Information System Specialist |
| GISS | Gone in Sixty Seconds (movie) |
| GISS | Gerencia de Informática de la Seguridad Social (Social Security Department for Information Technology Management; Spain) |
| GISS | Global Interconnect Sizing and Spacing |
| GISS | General Impression Shape and Size |
| GISS | Gordonstoun International Summer School (Scotland) |
| GISS | Guidance Interface Subsystem |
| GISS | Gosh, I’m So Surprised! (Sci-Fi fandom) |